Why do IVF fail many times?

(Dan Tri) - Many couples have failed IVF 3-4 times, even though the embryos are of good quality, the uterine lining is good, and test results are normal. What is the cause? What adjustments need to be made to increase the chances of success?

To provide a comprehensive perspective and update on the latest advances in infertility treatment, Dan Tri newspaper, in collaboration with Hong Ngoc Yen Ninh IVF Reproductive Support Center, is organizing an online seminar on the topic: "Multiple Failed In Vitro Fertilization (IVF) Procedures - Causes and Solutions".

The panel discussion will take place at 2 PM on July 4th, and will be broadcast live on Dan Tri newspaper and its Fanpage, with two guest speakers:

- Dr. Pham Thi Thuy Duong, Director of Hong Ngoc Yen Ninh IVF Reproductive Support Center.

- Dr. Nguyen Hong Hanh, MD, Clinical Doctor at Hong Ngoc Yen Ninh IVF Center.

Decoding the causes of IVF failure

According to experts, the success of an IVF procedure depends not only on embryo quality or endometrial thickness, but also on many more subtle factors such as sperm DNA fragmentation, misaligned implantation window, immune disorders, occult endometritis, and discharge from a previous cesarean section wound.

These factors are easily overlooked if not thoroughly and promptly screened.

Furthermore, repeating the same treatment regimen without analyzing the reasons for previous failures often leads many people into a vicious cycle, wasting time and money and significantly impacting their mental well-being.

This seminar is an opportunity for couples to better understand the IVF process, identify the factors that hinder success, and update themselves on modern assisted reproductive methods that are being effectively applied in Vietnam.

Experts will directly share their practical treatment experiences and provide in-depth analysis of over 15 typical cases submitted by readers to the program. Many cases had failed 3-4 times but still succeeded after making the right adjustments in the process.

A comprehensive perspective and practical approach for IVF patients.

Doctor Pham Thi Thuy Duong holds two twin babies from an IVF case (Photo: Hong Ngoc Hospital).

Beyond simply explaining the concept of IVF and existing methods, the seminar will help readers gain a deeper understanding of the reasons why many embryo transfers fail even when the embryos are of good quality, the uterine lining is stable, and test results are within normal ranges.

Seemingly minor factors that can have a significant impact, such as occult endometritis, sperm DNA fragmentation, immune disorders, or incorrect implantation window timing, will be clearly analyzed through real-life case studies from patients.

The program also updates on advanced support methods currently being applied in Vietnam, such as ERA testing to determine implantation timing, PRP therapy to improve the uterine lining environment, low-fragmentation sperm selection techniques, and immunological interventions tailored to each patient's condition.

A highlight of the seminar was the in-depth consultation session addressing over 15 specific case studies submitted by readers. Each story was a unique journey filled with anxieties, expectations, and even dead ends, raising the big question: Should I continue with IVF after multiple failures? If I try again, what changes are needed to increase the chances of success?

The program is aimed not only at couples currently undergoing IVF, but also at those who have experienced failure without finding the cause, as well as patients with underlying factors affecting fertility such as polycystic ovary syndrome, endometriosis, genetic abnormalities, or weak sperm.

This content is also useful for doctors, healthcare professionals, and anyone interested in the field of modern assisted reproductive technology.

Readers can ask questions to the experts here:

Source: https://dantri.com.vn/suc-khoe/vi-sao-lam-ivf-nhieu-lan-van-that-bai-20250703121122549.htm