The good news is that new research shows that mangoes have the ability to fight colorectal cancer, according to the medical site News Medical.
The study has just been published in the journal Science Scientific Reports, found that treatment with Mangiferin (MF), a natural compound abundant in mangoes, reduced the size and severity of colon adenomas and adenocarcinomas. Furthermore, it also reduces the number of abnormal tumors in the colorectal.
Colorectal cancer is the third most common type of cancer in the world
International research led by scientists from Al-Ahliyya Amman University (Jordan), University of Malaya (Malaysia), Jeddah University and Umm Al-Qura University (Saudi Arabia), Erbil Polytechnic University and Cihan-Erbil University (Iraq) collaborated to evaluate the anti-cancer effects of MF in mango on abnormal tumors in the colon and rectum mucosa in cancer-induced mice.
Metaplastic polyps form before colorectal polyps and are one of the earliest changes in the colon that can lead to cancer.
A total of 15 mice were subjected to carcinogenesis by injection of the carcinogen azoxymethane (AOM). The researchers observed that after injection of the carcinogen AOM, all mice developed multiple colon adenomas and adenocarcinomas with significant visceral metastasis, especially in the lymph nodes. blood in the intestines.
These mice were divided into 3 groups: Group 1 served as control, group 2 received a low dose of MF, and group 3 received a high dose of MF.
MF in mango has the ability to prevent colon cancer
The results showed that MF treatment reduced the size and extent of colon adenomas and adenocarcinomas. Furthermore, MF-treated mice had fewer total colorectal abnormalities than the control group. In particular, using low and high doses of MF are both safe and do not cause side effects, according to News Medical.
MF can be used as an alternative intervention to treat colorectal cancer, the researchers concluded.
Some studies have also documented the antioxidant, antifungal, analgesic, antibacterial, anti-diabetic, anti-inflammatory, and cardioprotective properties of MF.
