Scientists have just published a groundbreaking brain map that records detailed neural activity during decision-making, opening a new era for neuroscience.
Báo Khoa học và Đời sống•12/09/2025
This brain map was built from data from 139 mice, recording more than 600,000 neurons in 279 brain regions, accounting for about 95% of the entire mouse brain. Photo: Lifeboat Foundation. This is the first time scientists have had a comprehensive look at the neural activity as a decision is formed and carried out.
The achievement comes from the collaboration of 22 laboratories over 7 years, the results were published in the journal Nature on September 3. Research has two main directions: describing the broad distribution of neural activity during decision making, and analyzing the role of expectations in shaping choice.
The new map shows that decisions don't originate in just a few brain regions, but are the coordination of vast networks spread across the brain. Neuropixels technology, capable of recording signals from thousands of neurons at once, played a key role in creating this map. Experiments with mice performing a circular task on a screen have illustrated the neural process from visual signal reception, motor decision making to reward response.
Research also demonstrates that the brain uses knowledge and expectations from previous experiences early in information processing to make decisions.
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