
Online hemodiafiltration (HDF) is a modern blood filtration method that combines two mechanisms: hemodialysis and hemofiltration. While conventional dialysis primarily removes toxins with small molecular weights, online HDF is more effective at removing toxins with medium and large molecular weights – factors that cause many dangerous complications in patients with chronic kidney disease.
The highlight of this technique is the use of a high-flux filter along with a large amount of ultra-pure dialysis fluid generated directly from the dialysis machine. As a result, toxins that have accumulated in the body over time are removed more effectively, helping to reduce the burden on the patient's body and limit common acute and chronic complications.
At the Kidney and Dialysis Unit of the Provincial General Hospital, the online HDF method is currently being applied to many patients with end-stage chronic kidney disease undergoing cyclical hemodialysis. The new generation online HDF hemodialysis system from B.Braun has been invested in comprehensively, meeting all stringent technical and safety standards in treatment.
According to specialists, the implementation of online HDF has brought many positive changes for patients. One of the outstanding benefits is the reduction in the risk of cardiovascular complications – the leading cause of death in hemodialysis patients. This method helps improve hemodynamics and maintain more stable blood pressure during and after dialysis.
In addition, online HDF significantly reduces common unpleasant symptoms in kidney failure patients such as itching, chronic inflammation, body aches, and persistent fatigue. The effective removal of toxins such as β2-microglobulin, PTH, and phosphorus helps patients feel better after each dialysis session.

Dr. Nguyen Manh Tuan, Specialist II (Nephrology - Dialysis Unit, Provincial General Hospital), said: “Compared to conventional dialysis, online HDF helps patients experience less fatigue after dialysis, have a better appetite, and significantly improve their physical condition and quality of life. Many international studies also show that this method contributes to extending the lifespan of patients with chronic kidney disease.”
Not only does online HDF offer high treatment efficacy, but it also allows patients to access advanced techniques locally, reducing the burden of referrals to central hospitals. Importantly, patients receive treatment in accordance with professional regulations and are covered by health insurance as per current regulations.
To effectively implement this technique, the Provincial General Hospital has focused on investing in a high-purity RO water treatment system and dialysis fluid – a key factor determining safety in online HDF treatment. Along with this, a team of well-trained and experienced doctors, nurses, and technicians closely monitor each patient's condition to ensure optimal effectiveness in every dialysis session.
Mastering and routinely implementing online HDF technology further affirms the professional capacity of the Provincial General Hospital in the field of nephrology and dialysis. This is also an important step in the journey to improve the quality of medical examination and treatment, aiming to provide modern, safe, and humane medical services to the people in the province.
In the context of the increasing number of kidney failure patients, the application of advanced treatment techniques such as HDF online not only helps improve health and prolong life for patients, but also contributes to improving the quality of specialized medical care at the provincial level.
Source: https://baoquangninh.vn/loi-ich-thiet-thuc-tu-ky-thuat-loc-mau-hdf-online-3408205.html








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