First successful treatment of intersex patient with cryptorchidism

On May 30, Cho Ray Hospital ( Ho Chi Minh City) announced that for the first time in Vietnam, it successfully treated an intersex patient with hidden testicular cancer.

According to information from specialist doctor II Tran Trong Tri (Department of Urology, Cho Ray Hospital), patient A (40 years old, living in Dong Nai ) has a female appearance.

Ten days before being admitted to Cho Ray Hospital, the patient noticed that the left groin area began to grow larger and become more painful, so he went to a local hospital for examination and was then transferred to Cho Ray Hospital. The examination results showed that the patient's chest was not developed; there was no vagina... The mass in the left groin area was about 5x8cm, with a firm density, not mobile, and was not painful to the touch.

Assessing this as an extremely rare case, the treatment team held a multidisciplinary consultation and decided to perform surgery to remove the left testicular tumor. During the surgery, the doctors discovered that the patient still had a right ovary and no uterus. The pathological results were seminoma (a type of germ cell cancer in the testicles, commonly found in young men).

Specialist II Doctor Vuong Dinh Thy Hao, Deputy Head of Chemotherapy Department, Cho Ray Hospital shared: The patient had surgery, 6 cycles of supportive chemotherapy and all responded well, the disease improved.

Testicular cancer is a very common case in people whose testicles are hidden in the abdomen, especially in cases of gender disorder such as having two genital organs on the same body. It can be said that the patient was hospitalized for treatment late, however, fortunately, he was diagnosed, operated on and treated with chemotherapy successfully.

Doctor Vuong Dinh Thy Hao advised: "If patients and their relatives are unfortunately in this situation, do not hesitate to go to a medical facility with a urology department for timely examination, testing, and evaluation to avoid possible serious consequences, especially the very high risk of cancer in cases of hidden testicles in the abdomen."

Providing more information about this very rare case, Dr. Tran Trong Tri said that this case is classified in medical literature as mosaic true hermaphrodite. This is a disorder of sex differentiation characterized by the simultaneous presence of male and female genitalia in the same individual with a rate of 1/100,000 live births.

Mosaic hermaphroditism is a very rare form of anomaly. Mosaicism is thought to result from fusion of a fertilized egg with one of its polar bodies, binucleation, or double fertilization. The first case of mosaicism was reported in 1962 with true hermaphroditism, one ovary and one gonad. To date, there have been over 50 documented cases of true hermaphroditism and tumors in true hermaphroditism have been reported in less than 10 cases.

(According to HNMO)

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