VKIST successfully develops skin-mounted health monitoring biochip using cold plasma technology

The Vietnam-Korea Institute of Science and Technology (VKIST) has just organized an official ministerial-level acceptance of the scientific task “Developing cold plasma technology to coat functional materials on skin-mounted biochips for health monitoring applications”. This is a topic chaired by VKIST, aiming to create a technological foundation for smart biomedical sensors, supporting continuous and non-invasive health monitoring.

Overview of the Project acceptance session.

The acceptance council has 07 members, chaired by Prof. Dr. Nguyen Huu Lam, Head of the Department of Technical Physics, Hanoi University of Science and Technology.

In the context of smart medical devices playing an increasingly important role in personal health monitoring and care, the need to develop highly accurate, safe and user-friendly wearable biosensors is urgent. However, current sensors are still limited in terms of durability, biocompatibility and long-term performance when in direct contact with human skin. In response to this reality, the research team at VKIST proposed and implemented the task of "Developing cold plasma technology to coat functional materials on skin-mounted biochips for health monitoring applications", with the expectation of applying advanced cold plasma technology to create functional coatings to improve the efficiency and stability of non-invasive health monitoring devices.

The main objective of the mission is to apply cold plasma rays in the modification of the surface of supporting materials to enhance the ability to attach biological sensors to improve the sensitivity of sensor chips, thereby ensuring long-term health monitoring efficiency and safety for users.

At the acceptance meeting, MSc. Dau Huong Giang, project manager, on behalf of the research team, presented a summary of the project's results. Accordingly, the project achieved all of its objectives, including: (i) Designing and manufacturing a cold plasma device; (ii) Manufacturing a skin-mounted biochip to measure glucose in sweat; (iii) Manufacturing an electrochemical biochip to quantify %HbA1c in blood.

These results not only show the success of the project but also open up many potential application directions in medicine, industry and life.

The manual for the design and manufacture of cold plasma equipment can be fully applied to commercial production, serving many different purposes in several areas of life.

For the advanced sweat glucose measurement skin biochip product, using a microfluidic channel system, sweat samples are automatically taken into a reaction chamber containing a paper electrode. The presence of glucose in sweat is indicated by a blue color appearing on the paper electrode. Glucose concentration is easily determined by taking a photo of the paper electrode and uploading it to the website.

The electrochemical biochip product for quantifying %HbA1c in blood has good sensitivity and specificity, and fast analysis time.

Biochip products using cold plasma technology developed by VKIST scientists .

On behalf of the research team at VKIST, MSc. Dau Huong Giang, project manager, would like to thank the management agencies and relevant agencies for their many comments and suggestions for the project; for their consideration and support in completing the products in the correct quantity and quality as required by the order. The comments are not only of scientific value but also of high practical significance, so the research team needs to absorb, complete the project and continue to research in the following projects.

Prof. Dr. Nguyen Huu Lam, Chairman of the Mission Council, spoke.

In his concluding remarks, based on the consensus of the Council members, Prof. Dr. Nguyen Huu Lam, Chairman of the Council, highly appreciated the efforts of the research team in implementing the experiment on the real model, obtaining clear quantitative results, and at the same time, said that this was a scientific research project that was carefully and seriously carried out, successfully completing the objectives and tasks of the proposed research. Some comments also recommended that the research team continue to develop towards commercialization of the product, especially in coordination with businesses in the medical equipment industry to perfect the process and expand the scope of application.

The topic has been evaluated and classified by the Acceptance Council as: Passed.

Vietnam - Korea Institute of Science and Technology

Source: https://mst.gov.vn/vkist-phat-trien-thanh-cong-chip-biology-theo-doi-suc-khoe-gan-tren-da-su-dung-cong-nghe-plasma-lanh-197250718164106671.htm