New step forward in Vietnamese biomedical materials science

In the context of the increasing need for treatment of bone injuries due to accidents, diseases and population aging, the development of safe, effective and domestically produced bone graft materials has become an urgent requirement of the medical industry.

The scientific task "Research on manufacturing composite materials based on tri-calcium phosphate, hydroxyapatite and alpha-calcium sulfate hemihydrate for use as bone regeneration materials" (code DTĐL.CN-35/22), chaired by Prof. Dr. Nguyen Dai Hai, has marked an important step forward in the field of biomedical materials in Vietnam.

Under the National Technology Development and Applied Research Program, the overall objective of the project is to synthesize and master the technology to manufacture a number of artificial bone graft materials that can be applied in regenerative medicine. Two specific objectives include: Developing technology to manufacture composite materials based on superior bio-inorganic materials and evaluating preclinical safety, aiming to gradually move towards clinical application.

New step forward in Vietnamese biomedical materials science.

With the in-depth research capacity of the Institute of Advanced Technology (Vietnam Academy of Science and Technology), the team has successfully optimized the synthesis process of composite materials including tri-calcium phosphate (TCP), hydroxyapatite (HAp) and alpha-calcium sulfate hemihydrate, components with similar structures to natural bone minerals. This combination helps the material achieve high biocompatibility, suitable biodegradability and supports the regeneration of new bone tissue.

Not only stopping at research and manufacturing, the research team has conducted a comprehensive assessment of safety and effectiveness through preclinical trials. The results show that the composite material has a high level of safety, is not cytotoxic, and stimulates the ability to form new bone at the implant site. This is an important preparation step for future clinical research and commercialization.

The project brings new contributions of great significance to the development of the biomedical materials industry. In the context of the Government's special interest in the field of regenerative medicine, the research results contribute to building a solid scientific and technological foundation for the development of "Make in Vietnam" implant materials. This not only meets domestic treatment needs but also opens up potential directions for businesses when participating in the high-value medical equipment market.

Mastering bone regeneration materials.

The mission also contributes to the formation of a domestic biomedical materials research and production ecosystem through promoting technology transfer, product commercialization and strengthening links between research institutes, hospitals and businesses. This is a key factor to help the Vietnamese biomedical materials industry improve its competitiveness in the future.

In terms of economic efficiency, mastering the technology of manufacturing bone grafting materials will bring great benefits to businesses and the market. The optimal production process helps reduce costs, improve quality and diversify products, thereby increasing competitiveness compared to imported goods. In the context that many medical materials still depend on foreign supplies with high costs, domestic products will help reduce the cost burden for patients, shorten import time and ensure stable supply.

The social impact of the project is even more evident as the research results open up opportunities to provide affordable and more accessible implant materials to people, especially in provincial hospitals and rural areas. The success of the project also motivates businesses to invest in pilot production, gradually forming a domestic value chain in the field of biomedical materials. At the same time, the research team's professional capacity is enhanced, contributing to the training of high-quality human resources for the medical and materials technology sectors.

With the results achieved, the DTĐL.CN-35/22 mission not only has scientific significance but also has profound practical value for the Vietnamese regenerative medicine industry. Mastering bone regeneration materials is an important first step towards self-sufficiency in the production of medical equipment, contributing to improving the quality of public health care and promoting the development of the domestic biomedical industry.

Center for Science and Technology Communication

Source: https://mst.gov.vn/buoc-tien-moi-cua-khoa-hoc-vat-lieu-y-sinh-viet-nam-197251201105924529.htm