Discovering the "Next-Generation Viagra" from the creature men fear most.

The terrifying creature in question is the Phoneutria nigriventer spider, also known as the "banana spider," which possesses an extremely potent venom that can cause priapism—a prolonged erection—in mammals, including humans.

The poisoning can be severe enough to cause necrosis of penile tissue, posing a life-threatening risk, and in some cases, amputation is necessary.

However, scientists from the Federal University of Minas Gerais (Brazil) have discovered a spectacular application for that very deadly venom.

Tìm ra “Viagra thế hệ mới” từ sinh vật quý ông sợ nhất - Ảnh 1.

BZ371A gel derived from spider venom promises to create a new generation of erectile dysfunction treatment - Illustration from the Internet

In a new study, scientists have invented a gel called BZ371A, which is now in phase 2 (on animals) trials, according to Science Alert .

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This gel, which can be applied to the groin to help activate an erection, holds promise as the next-generation treatment for erectile dysfunction.

Scientists have discovered that the principle behind the dangerous priapism caused by banana spider venom is the activation of nitric oxide release in the body, which in turn increases blood flow to the genitals.

If attacked directly by a spider, the victim receives too much venom, causing this mechanism to become excessive and dangerous. Therefore, using a small amount can help achieve an erection for a shorter period of time.

This mechanism that triggers the release of nitric oxide is also the primary mechanism of action of the well-known erectile dysfunction drug Viagra.

A small pilot trial involving both men and women showed that the "spider venom gel" BZ371A appeared easier to use than Viagra, avoiding adverse effects for some individuals with underlying health conditions.

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Larger clinical trials are still being planned, starting with a number of men with erectile dysfunction.

Scientists also stated that this drug has the potential to be used in women with sexual dysfunction, which will be considered in subsequent trials.