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Warning of adverse reactions when patients with chronic kidney disease and cancer use drugs

(Dan Tri) - Experts warn that physiological changes due to illness can cause people with chronic kidney disease to experience more adverse reactions to medication than normal people.

Báo Dân tríBáo Dân trí15/06/2025

Speaking at the Southern Regional Pharmacovigilance Conference 2025, which took place for 2 days in mid-June in Binh Thuan province, Dr. Nguyen Quoc Binh, Deputy Director of Cho Ray Hospital, emphasized the importance of connecting pharmacovigilance and clinical pharmacy activities.

That is because currently, the rate of chronic kidney disease and cancer in Vietnam is increasing.

According to the latest epidemiological data, chronic kidney disease is becoming one of the most serious public health burdens globally. It is estimated that 10-13% of the world's population, equivalent to 800-850 million people, is affected by this disease.

According to Dr. Binh, the use of drugs becomes complicated in the treatment of kidney diseases and impaired kidney function.

Cảnh báo phản ứng bất lợi khi người bệnh thận mạn, ung thư sử dụng thuốc - 1

Dr. and pharmacist Nguyen Quoc Binh (left cover) shared at the conference (Photo: BV).

Patients with chronic kidney failure need to take many medications, and physiological changes due to the disease can also cause patients to experience more adverse reactions to medication than normal people.

In the field of cancer treatment, chemotherapy and targeted therapy are highly effective for patients, but also come with high toxicity. The drugs often have a narrow therapeutic window, require high doses and strict adherence to the regimen, making patients susceptible to serious side effects.

According to the latest GLOBOCAN data, in 2022, the world recorded about 20 million new cancer cases and is expected to increase to 21 million cases. In Vietnam, there are currently about 190 thousand new cancer cases.

Dr. Nguyen Quoc Binh, who is currently the Director of the Ho Chi Minh City Drug Information and Adverse Drug Reactions Center (DI&ADR), emphasized that with the above situation, comprehensive, appropriate and effective treatment strategies are required.

In which, pharmacovigilance and clinical pharmacy play a pivotal role in ensuring safety and optimizing treatment effectiveness for patients.

Cảnh báo phản ứng bất lợi khi người bệnh thận mạn, ung thư sử dụng thuốc - 2

A patient is being treated after a kidney transplant at Cho Ray Hospital (Photo: BV).

The Southern Regional Pharmacovigilance Conference 2025 with the theme "Connecting pharmacovigilance - clinical pharmacology in kidney diseases and cancer" includes 1 plenary session and 4 thematic sessions.

The discussion sessions revolved around the fields of Pharmacy - Nephrology, Artificial Kidney, Oncology, Kidney Transplantation, with 44 in-depth reports.

The program brings highly practical topics such as: Update on diagnosis and treatment of chronic kidney disease; Rational use of drugs in patients with kidney disease; Combining pharmacovigilance - clinical pharmacy at Cho Ray Hospital; Post-vaccination reactions; Increased kidney filtration and drug metabolism...

In particular, the Conference also had the participation of 2 speakers who are foreign experts, with 2 in-depth reports on the topics "Rational use of drugs in kidney transplantation" and "Integration of clinical pharmacy in cancer: From practice to real value".

Source: https://dantri.com.vn/suc-khoe/canh-bao-phan-ung-bat-loi-khi-nguoi-benh-than-man-ung-thu-su-dung-thuoc-20250615114036022.htm


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