How exercise doubles the effectiveness of cancer drugs

Scientists at the Universities of Birmingham and Bath (UK) wanted to test the impact of exercise on the effectiveness of the drug Rituximab - an antibody therapy used to treat chronic lymphocytic leukaemia (CLL) - a type of blood cancer. This is a common treatment for CLL.

When people exercised moderately to vigorously, their number of cancer-killing killer cells increased by 254 percent.

The trial included 20 CLL patients, aged 45 to 82, who had not received treatment for the disease.

Participants were asked to cycle at a moderate to vigorous intensity for 30 minutes.

At the same time, blood samples were taken before, immediately after exercise, and 1 hour later.

The results found that after moderate to vigorous exercise, the number of cancer-killing killer cells in patients increased by a surprising 254 percent, according to Science Daily.

Notably, in the next step of the trial - looking at the effectiveness of the cancer drug Rituximab after exercise, the authors found that after moderate to vigorous exercise, the effectiveness of Rituximab in killing cancer cells doubled, according to Science Daily.

This is the first study to show that a single bout of moderate to vigorous exercise improves the effectiveness of the cancer drug Rituximab, the authors write.

A single bout of moderate-to-vigorous exercise not only increases the number of killer cells that attack cancer cells, but also doubles the effectiveness of cancer drugs

At the same time, the results also showed that after moderate to vigorous exercise, the amount of cancer cells entering the blood also increased by 67% compared to before exercise. This has great significance in finding and destroying cancer cells, because according to the lead author of the study, Dr. John Campbell, at the University of Bath, cancer cells often try to "hide", "chasing" cancer cells into the blood helps increase the effectiveness of antibody therapy and increase the ability of killer cells to destroy.

However, the authors note: Although these results are promising, larger trials are needed before treatment recommendations can be made.

There is growing evidence that exercise can stimulate the body's immune cells to fight cancer cells.

However, cancer treatment can cause extreme fatigue and hinder physical activity, making vigorous exercise actually quite difficult for people with cancer.

Source: https://thanhnien.vn/cach-tap-the-duc-lam-tang-gap-doi-hieu-qua-cua-thuoc-dieu-tri-ung-thu-185240610090515037.htm