Scientists have discovered that skin cells have the ability to switch between solid and liquid states to promote scar healing - Illustration: GETTY IMAGES
Have you ever wondered what happens when a small cut heals? Professor Cédric Blanpain's team at the Free University of Brussels (ULB) dug into this question and made a surprising discovery.
By directly observing the wound healing process in mice under a microscope, they discovered that skin cells do not simply migrate to fill the wound, but also undergo a very special state transformation process.
According to research published in the journal Cell , skin cells are initially in a solid state. However, when there is a wound, they "melt" into a liquid form, allowing them to move easily and quickly to the site of repair.
Once their job is done, these cells "freeze" to form new skin tissue.
This transition between solid and liquid states is likened to a biological “gel.” Scientists have identified the genetic factors that play a key role in controlling this transition. They can even use drugs to temporarily block this process and keep cells in a liquid state.
This discovery opens up new possibilities for treating chronic wounds such as diabetic ulcers, pressure ulcers and diseases that involve tissue remodeling. By understanding the mechanisms of scar healing, scientists can develop more effective treatments that help wounds heal faster and minimize scarring.
The research also has important implications for the field of regenerative medicine. Scientists are looking at ways to stimulate tissue regeneration in other organs such as the heart, liver, and lungs. Understanding the mechanism of skin healing could provide important implications for research on regenerating these tissues.
Many questions remain. For example, how can we speed up the healing of large wounds? Does this cell-state transition occur in other types of tissue? And how can we control this process more precisely?
However, the team’s findings offer a completely new perspective on the process of scar healing. This is an important step forward in understanding the body’s self-healing mechanism and opens up new directions for treating wound-related diseases.
Source: https://tuoitre.vn/phat-hien-dot-pha-ve-qua-trinh-lien-seo-20240816142942721.htm
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