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Researchers from Lanzhou University Hospital and Nanchang Hangkong University, China, have developed a new cancer treatment technique using fluorescent functional materials that is effective and inexpensive. The research results were published in the Chemical Engineering Journal.
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| Image of a fluorescently stained cancer cell |
The rapid development of advanced optical technologies for cancer diagnosis and treatment using fluorescent sensing and bioimaging requires a variety of highly efficient fluorescent materials, said researcher Liu Tao of Lanzhou University Hospital. The research team designed and synthesized a series of cyanostyrene-based synthetic luminogens (AIEgens) by combining electron donors and fluorescent depleting groups.
The researchers also demonstrated the excellent performance of AIEgen in fluorescence sensing, organelle imaging, and photodynamic therapy. This study provides a new approach for the development of more sensitive, stable, and tunable fluorescent materials. The research will contribute to clearer imaging of cancer cells, thereby providing more accurate treatment regimens.
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