Sweden develops antibodies with potential to treat cancer.

A team of researchers from Uppsala University and the Royal Institute of Technology KTH in Sweden has developed a new antibody that has the potential to treat a variety of different cancers.

A doctor is examining a mammogram - Photo: Reuters

According to GlobalData , with this new method, researchers have combined three different functions in antibodies, which are believed to enhance the effect of T cells on cancerous tumors.

Antibodies help identify cancer cells.

These antibodies can guide the immune system to recognize and attack "neoantigens," which are mutations and gene changes that only appear in cancer cells.

The dual mechanism of antibodies involves delivering tumor-specific materials to immune cells and stimulating them to enhance the T-cell response.

The potential of this method has been demonstrated in both human blood samples and animal models, according to the researchers.

Studies have shown that antibodies can properly activate immune cells and prolong the lifespan of mice. At higher doses, the antibodies helped mice recover from cancer and were deemed safer than previous cancer treatments.

The research results show that this method can be adapted to suit each patient in order to boost the immune system's ability to fight cancer.

Precision medicine methods for cancer treatment.

Professor Sara Mangsbo from the Faculty of Medicine, Uppsala University, said: "We have been researching precision medicine for almost 15 years, as well as how to use antibodies to influence a key protein (CD40) in the immune system. We can now show that this new antibody approach works as a precision medicine approach for cancer treatment."

The next step in antibody development will be to use a fully optimized manufacturing process to produce the drug for additional safety studies, and then to launch clinical trials in humans for cancer treatment.

Professor Johan Rockberg of the Royal Institute of Technology (KTH) shared: "The advantage of the drug we are researching is that it is easy to produce on a large scale and can be easily tailored to the specific disease or tumor of a patient."

Source: https://tuoitre.vn/thuy-dien-phat-trien-khang-the-co-tiem-nang-dieu-tri-ung-thu-20241115234138141.htm